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Table 1 N-Cre: Mbd3 flox/flox peri-natal mortality

From: The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex

  Percentage (%)
d.p.c. N-Cre: Mbd3 Flox/+ Mbd3 Flox/+ Mbd3 Flox/Flox N-Cre: Mbd3 Flox/Flox N
12.5 25 12.5 25 20.8 24
14.5 25.9 25.9 14.8 22.2 27
15.5 50 25 12.5 12.5 16
16.5 17.5 35 29.1 14.6 57
17.5 36.4 18.2 22.7 22.7 22
Postnatal 28.4 40.8 29.6 0.8a 250
  1. aAll N-Cre:Mbd3 Flox/Flox mice born live were found dead within 24 h after birth. Genotypes of pups and embryos produced from N-Cre(Flox/+) × (Flox/Flox) intercrosses recovered at indicated time points.
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Neural Development

ISSN: 1749-8104